Factors that mediate colonization of the human stomach byHelicobacter pylori
نویسندگان
چکیده
منابع مشابه
Multiple Acid Sensors Control Helicobacter pylori Colonization of the Stomach
Helicobacter pylori's ability to respond to environmental cues in the stomach is integral to its survival. By directly visualizing H. pylori swimming behavior when encountering a microscopic gradient consisting of the repellent acid and attractant urea, we found that H. pylori is able to simultaneously detect both signals, and its response depends on the magnitudes of the individual signals. By...
متن کاملThe dynamics of Helicobacter pylori infection of the human stomach.
Helicobacter pylori is a bacterial pathogen of the gastrointestinal tract of humans causing chronic superficial gastritis which persists for decades. The mechanism by which H. pylori is able to persist, despite environmental constraints, remains unknown. Therefore, a model is proposed describing the interactions of H. pylori with its host, involving an autoregulatory network in which inflammati...
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Helicobacter pylori infection is a risk factor for development of peptic ulcers, and psychological stress (PS) may have a role in the pathogenesis of this condition. However, no interaction between PS and H. pylori infection (HI) has been established in the development of peptic ulcer, because colonization by H. pylori is the first step in the infection of the gastric mucosa, we examined H. pyl...
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BACKGROUND The bacterium Helicobacter pylori is able to adhere to and to colonise the human gastric epithelium, yet the primary gene product responsible as a receptor for its adherence has not been identified. AIMS To investigate the expression of the gastric mucins MUC5AC and MUC6 in the gastric epithelium in relation to H pylori colonisation in order to examine their possible roles in the b...
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Helicobacter pylori (H. pylori) is a pathogen contributing to peptic inflammation, ulceration, and cancer. A crucial step in the pathogenic sequence is when the bacterium first interacts with gastric tissue, an event that is poorly understood in vivo. We have shown that the luminal space adjacent to gastric epithelial damage is a microenvironment, and we hypothesized that this microenvironment ...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i19.5610